Zonegran (Cont.)

Effects of Zonegran

Three studies have shown that Zonegran is effective for treating partial seizures in adults whose seizures were not adequately controlled by other seizure medications. In these studies, people added Zonegran or a placebo ("sugar pill") to the seizure medications they were already taking. Those who added Zonegran decreased their rates of partial seizures by up to 40.5 percent, compared to just 9 percent in those who added the placebo to their seizure medications.
 

When and How to Take Zonegran

General considerations for when and how to take Zonegran include the following:
 
  • The medication comes in capsule form and is taken by mouth once or twice daily.
  • Usually, you will start with a low Zonegran dose and slowly increase up to an effective one.
  • Be sure to swallow the capsules whole (do not chew, crush, or open them).
  • Zonegran can be taken with or without food. If the medication bothers your stomach, try taking it with food.
  • Zonegran should be taken at the same time each day to maintain an even level in your blood.
  • For the medication to work properly, it must be taken as prescribed. Zonegran will not work if you stop taking it.
  • Do not stop taking Zonegran without first discussing it with your healthcare provider (see Zonegran Withdrawal).
     

Dosing Information for Zonegran

The dose of Zonegran that your healthcare provider recommends will vary, depending on a number of factors, including:
 
  • Other medications you may be taking (especially other seizure medications)
  • Other medical conditions you may have.
     
As is always the case, do not adjust your Zonegran dose unless your healthcare provider specifically instructs you to do so.
 
(Click Zonegran Dosage for more information.)
 
(Zonegran Continued: Page 3)

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;