Zonegran Drug Interactions

Zonegran drug interactions can occur when the seizure medication is taken with Luminal, Dilantin, or a number of other drugs. These interactions can lead to problems such as decreased drug levels in the blood. To learn more about the specific Zonegran drug interactions that apply to you, be sure to talk to your healthcare provider.

Zonegran Drug Information

An Overview of Zonegran Drug Interactions

Zonegran^® (zonisamide) can potentially interact with other medications, particularly other seizure medications. Some of the medicines that may lead to Zonegran drug interactions include:

Carbamazepine (Carbatrol^®, Epitol^®, Equetro™, Tegretol^®)
Phenobarbital (Luminal^®)
Phenytoin (Dilantin^®, Phenytek^®)
Primidone (Mysoline^®).

Zonegran Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Zonegran is combined with any of the drugs listed above.

Carbamazepine

Carbamazepine can decrease the level of Zonegran in your blood, perhaps making it less effective. Your healthcare provider will recommend a higher Zonegran dosage if you are taking carbamazepine, and may lower your dosage if you stop taking carbamazepine.

Phenobarbital

Combining Zonegran with phenobarbital can decrease the level of Zonegran in your blood, possibly making it less effective. Your healthcare provider will recommend a higher Zonegran dosage if you are taking phenobarbital, and may lower your dosage if you stop taking phenobarbital.

Phenytoin

Phenytoin can decrease the level of Zonegran in your blood, perhaps making it less effective. Your healthcare provider will recommend a higher Zonegran dosage if you are taking phenytoin, and may lower your dosage if you stop taking phenytoin.

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