Drug Interactions With Valproic Acid

Amitriptyline
Valproic acid can raise the level of amitriptyline in your blood, potentially increasing your risk of amitriptyline side effects. If you are taking these drugs together, your healthcare provider may need to decrease your amitriptyline dosage.
 
Aspirin
Aspirin may affect the way your body handles valproic acid, perhaps increasing your risk of side effects. If you are taking these drugs together, your healthcare provider will need to monitor you more closely and adjust your valproic acid dosage as necessary.
 
Carbamazepine
Taking carbamazepine with valproic acid can decrease the level of valproic acid in your blood, perhaps making it less effective. Taking these medications together may also affect the way your body handles carbamazepine, potentially increasing your risk of side effects. If you are taking valproic acid along with carbamazepine, your healthcare provider will monitor you more closely and adjust your dose of these medications, if necessary.
 
Chlorpromazine
Chlorpromazine can raise the level of valproic acid in your blood, increasing your risk of side effects. If you are taking these drugs together, your healthcare provider may need to decrease your valproic acid dosage to prevent interactions from occurring.
 
Clonazepam
Combining clonazepam with valproic acid can increase your risk of absence seizures, especially if you have had absence seizures before. Talk with your healthcare provider before taking these medications together.
 
Diazepam
Valproic acid can increase the level of diazepam in your blood, increasing your risk of diazepam side effects. If you are taking these medications together, your healthcare provider may need to decrease your diazepam dosage.
Know the Signs - Concussion Safety

Valproic Acid Drug Information

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