Trileptal Drug Interactions (Cont.)

 
Felodipine (Plendil)
Trileptal can decrease the level of felodipine in your blood, perhaps making it less effective. If you are taking Trileptal together with felodipine, your healthcare provider may need to increase your felodipine dosage.
 
Oral Contraceptives
Trileptal may make oral contraceptives (birth control pills) less effective. Talk with your healthcare provider about the best methods of birth control if you are taking Trileptal.
 
Phenobarbital (Luminal)
Combining phenobarbital with Trileptal can increase the level of phenobarbital and decrease the level of Trileptal in your blood. If you are taking phenobarbital along with Trileptal, your healthcare provider may need to adjust your doses of these medications.
 
Phenytoin (Dilantin, Phenytek)
Combining phenytoin with Trileptal can increase the level of phenytoin and decrease the level of Trileptal in your blood. If you are taking phenytoin along with Trileptal, your healthcare provider may need to adjust your doses of these medications.
 
Valproic Acid (Depakene) or Divalproex Sodium (Depakote, Depakote ER)
Valproic acid or divalproex sodium can decrease the level of Trileptal in your blood, perhaps making it less effective. If you are taking Trileptal together with valproic acid or divalproex sodium, your healthcare provider may need to adjust your doses of these medications.
 
Verapamil (Calan, Calan SR, Covera-HS, Isoptin SR, Verelan, Verelan PM)
Verapamil can decrease the level of Trileptal in your blood, perhaps making it less effective. If you are taking verapamil along with Trileptal, your healthcare provider may need to adjust your doses of these medications.
 
(Trileptal Drug Interactions Continued: Page 3)

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;