Tranxene

Tranxene is a benzodiazepine that has been approved to treat anxiety, alcohol withdrawal, and seizures. The medication works by enhancing the effects of a specific calming chemical in the brain. As a result, it can reduce anxiety, stop seizures, and relax muscles. Tranxene comes in both short-acting and long-acting forms. Common side effects include drowsiness, dizziness, and upset stomach.

 

What Is Tranxene?

Tranxene® (clorazepate dipotassium) is a prescription medication that is used to treat the following conditions:
 
(Click Tranxene Uses for more information, including possible off-label uses.)
 

Who Makes Tranxene?

Tranxene is currently made by Ovation Pharmaceuticals.
 

How Does Tranxene Work?

Tranxene is part of a group of medicines known as benzodiazepines. Benzodiazepines have several different effects on the body, including:
 
  • Stopping seizures
  • Reducing anxiety
  • Causing sleepiness
  • Relaxing muscles
  • Impairing short-term memory.
     
All benzodiazepines can have these effects to some degree, depending on the specific medication and the dosage. They work in the brain by enhancing the effects of gamma-aminobutyric acid (GABA), a brain chemical that is naturally calming. GABA can slow down or stop certain nerve signals in the brain. This is why Tranxene and other benzodiazepines are known as mild tranquilizers, sedatives, or central nervous system depressants (CNS depressants).
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;