Topamax Drug Interactions

To reduce the risk of developing Topamax drug interactions, make sure to tell your healthcare provider about all other medications you are currently taking. Medicines that may cause drug interactions with Topamax include metformin, oral contraceptives, hydrochlorothiazide, and pioglitazone. These interactions can potentially reduce the effectiveness of the drugs or lead to side effects such as excessive drowsiness, kidney stones, confusion, and decreased sweating.

 

Topamax Drug Interactions: An Overview

Topamax® (topiramate) can potentially interact with a few other medicines. Some of these medicines that may lead to Topamax drug interactions include:
 
  • Alcohol or medications that can cause drowsiness ("CNS depressants")
  • Amitriptyline (Elavil®)
  • Carbonic anhydrase inhibitors, such as:
o Acetazolamide (Diamox®)
o Dichlorphenamide (Daranide®)
o Methazolamide
(Topamax Drug Interactions Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;