Topamax Dosage

Topamax Dose for Epilepsy (Adjunctive Therapy)

The recommended dose of Topamax for epilepsy as adjunctive therapy (in combination with other epilepsy medications) varies, depending on the person's age and the type of seizures. For people age 17 and over, the recommended dose is 100 mg to 200 mg twice daily for partial seizures, or 200 mg twice daily for generalized tonic-clonic seizures. The dose should be slowly increased up to the recommended dose, as when used for monotherapy.
 
For children age 2 to 16, the recommended dose is 5 mg to 9 mg per kg of weight (about 2.3 to 4 mg per pound), split into two doses per day. The starting Topamax dosage should be low and increased slowly as directed by your child's healthcare provider.
 

General Information on Dosing With Topamax

Some considerations for people taking Topamax include the following:
 
  • Topamax comes in tablets or "sprinkle" capsules. It is taken by mouth, usually twice a day.
     
  • The sprinkle capsules can be opened and the contents sprinkled on a spoonful of soft food and swallowed (not chewed) immediately. They can also be swallowed whole.
     
  • You can take the medication with or without food.
     
  • For people with kidney disease (such as kidney failure), the recommended dose is lower (half the usual dose).
     
  • Topamax should be taken at the same times each day to maintain an even level in your blood.
     
  • For the medication to work properly, it must be taken as prescribed. Topamax will not work if you stop taking it.
     
  • If you are unsure about anything related to your Topamax dosage, please talk to your doctor, nurse, or pharmacist.
     
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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