Drug Interactions With Primidone

Some of the drugs that can interact with primidone include anesthetics, barbiturates, and sleep medications. Some of these potential drug interactions with primidone can change the amounts of the medications in your blood, possibly increasing your risk of side effects or decreasing the effectiveness of the drugs. Prior to starting primidone, it is important to consult your healthcare provider to be sure you understand the specific interactions that may apply to you.

An Overview of Drug Interactions With Primidone

Primidone (Mysoline®) can potentially interact with other medications. Some of these medicines that may lead to primidone interactions include:
  • Alcohol
  • Anesthetics
  • Antidepressant medications
  • Barbiturates, such as:


    • Amobarbital (Amytal®)
    • Butalbital (Fioricet®, Fiorinal®)
    • Pentobarbital (Nembutal®)
    • Phenobarbital (Luminal®)
    • Secobarbital (Seconal®


  • Benzodiazepines, including:



  • Certain antifungal medications, including:


    • Fluconazole (Diflucan®)
    • Itraconazole (Sporanox®)
    • Ketoconazole (Nizoral®)
    • Voriconazole (Vfend®)


Know the Signs - Concussion Safety

Primidone Drug Information

Referring Pages:
Terms of Use
Advertise with Us
Contact Us
About eMedTV
Privacy Policy
Copyright © 2006-2019 Clinaero, Inc.
eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click Terms of Use for more information.