Drug Interactions With Primidone

HIV or AIDS Medications
Taking primidone with an HIV or AIDS medication can affect the level of both medications in your blood, perhaps increasing your risk of side effects or making the medications less effective. Talk to your healthcare provider before taking primidone with an HIV or AIDS medication. Your healthcare provider may need to monitor you more closely.
 
Hormonal Contraceptives
Primidone can decrease the level of hormonal contraceptives (birth control) in your blood, increasing your risk of unintentional pregnancy. Talk with your healthcare provider about the best form of birth control for women taking primidone.
 
Narcotics or Opiates
Combining an opiate or narcotic with primidone can increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious side effects may occur. Make sure to talk to your healthcare provider before taking primidone with an opiate or narcotic.
 
Other Seizure Medications
Combining primidone with other seizure medications can increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Also, primidone can affect the level of other seizure medications in your blood. Make sure to talk to your healthcare provider before taking primidone with another seizure medication, as you may need to be monitored more closely.
 
Sleep Medications
Combining a sleep medication with primidone can increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious side effects may occur. Make sure to talk to your healthcare provider before taking primidone with a sleep medication.
 

Final Thoughts on Drug Interactions With Primidone

It is possible that not all primidone drug interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about any specific drug interactions with primidone that may apply to you.
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