Phenytek Drug Interactions

Phenytek can interact with several substances, including alcohol, digoxin, and calcium. Some of these Phenytek drug interactions can alter the amounts of the medications in your blood, potentially increasing your risk of side effects or decreasing the effectiveness of the drugs. Because Phenytek can interact with so many medications, it is important to tell your healthcare provider any time you start, stop, or change your dose of any medication.

 

An Overview of Phenytek Drug Interactions

Phenytek® (phenytoin sodium) can potentially interact with many other medications. Some of the medicines that may lead to Phenytek interactions include:
 

 

 

 

 

  • Quinidine
  • Reserpine
  • Rifampin (Rifadin®)
  • Salicylates, such as aspirin (Ecotrin®, Bayer®, Anacin®), choline magnesium trisalicylate (Trilisate®), diflunisal (Dolobid®), and salsalate (Salflex®, Disalcid®, Amigesic®)
  • Sucralfate (Carafate®)
  • Sulfonamides ("sulfa drugs"), such as sulfadiazine, sulfadoxine (Fansidar®), sulfamethoxazole (Bactrim®, Septra®), and sulfisoxazole (Gantrisin®)
  • Ticlopidine (Ticlid®)
  • Theophylline (Uniphyl®, Theocron®, TheoCap®, Theo-24®, Elixophyllin®)
  • Tolbutamide (Orinase®)
  • Trazodone (Desyrel®)
  • Valproic acid (Depakene®) or divalproex sodium (Depakote®, Depakote ER®)
  • Warfarin (Coumadin®, Jantoven®).
     
(Phenytek Drug Interactions Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;