Onfi Warnings and Precautions

It is important for your doctor to know if you have depression, breathing problems, or a history of drug or alcohol abuse before starting treatment with Onfi. Other safety precautions include warnings of an increased risk for suicidal thoughts, as well as physical and psychological dependence. Also, Onfi can interfere with many other medications and may not be safe for women who are pregnant or breastfeeding.

What Should I Tell My Healthcare Provider?

Talk with your healthcare provider prior to taking Onfi™ (clobazam) if you have:
  • A history of drug or alcohol abuse
  • Depression
  • Breathing problems
  • Any allergies, including to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
You should also tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.

Specific Warnings and Precautions With Onfi

Some warnings and precautions to be aware of prior to taking this medicine include the following:
  • Studies suggest that seizure medications may increase the risk for suicide. Make sure to watch for any unusual behaviors or mood changes, and be sure your family and friends know to keep an eye out for such problems.
  • Onfi is a controlled substance, which means it has the potential to be abused. There are special rules and regulations for prescribing and dispensing Onfi. This medicine should be used with caution in people with a history of alcohol or drug abuse.
  • Onfi can cause extremely dangerous reactions that often start with a skin rash. Report any rash in a person taking this drug to a doctor immediately, unless it is very clear that the rash is caused by something else. Be especially vigilant for rashes in the first eight weeks of treatment.
  • Because Onfi can cause physical and psychological dependence, you should not stop taking the drug suddenly without first discussing it with your healthcare provider. He or she can gradually decrease your dosage over several weeks to help wean you off the medication.
  • Onfi can cause severe drowsiness and difficulty breathing, which can be fatal. This risk is increased when Onfi is combined with alcohol, narcotics, or other medications or substances that cause drowsiness and sedation (see Onfi Drug Interactions for more information). You should not drive or operate heavy machinery until you know how this drug will affect you.
  • Onfi is a pregnancy Category C medication. This means that it may not be safe for use during pregnancy, although the full risks are currently unknown (see Onfi and Pregnancy).
  • Onfi passes through human breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking the drug (see Onfi and Breastfeeding).
Know the Signs - Concussion Safety

Onfi Medication Information

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