Your specific dose of Onfi will depend on factors such as your age and weight, other medical conditions you may have, and other medications you are taking. Although the drug is more effective at higher doses, these amounts can increase your risk for side effects. In general, a person is started at a lower dose, and the amount is gradually increased.
The dose of Onfi™ (clobazam) your healthcare provider recommends will vary, depending on a number of factors, including:
- Your age and weight
- Other medications you are taking
- Other medical conditions you may have.
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.
There is no one "set-in-stone" way to dose this medication. The drug is more effective at higher amounts; however, higher dosages of any medication usually come with a higher risk for side effects. No matter how the drug is dosed, a lower amount should be used initially, with dose increases occurring at intervals of at least one week or more.
One suggested way is as follows, for individuals weighing 66 pounds (30 kg) or less:
- Days 1 through 6 -- 5 mg once daily
- Days 7 through 13 -- 5 mg twice daily
- Days 14 and beyond -- 10 mg twice daily.
For individuals weighing more than 66 pounds, one recommended way is as follows:
- Days 1 through 6 -- 5 mg twice daily
- Days 7 through 13 -- 10 mg twice daily
- Days 14 and beyond -- 20 mg twice daily.
If you have liver disease, are elderly, or are taking certain medications that interact with Onfi (see Onfi Drug Interactions), lower doses may be recommended.
Do not stop taking Onfi suddenly, as severe withdrawal symptoms may occur. Your healthcare provider will help you gradually lower your dose over a period of several weeks.