Neurontin

Neurontin is a medication commonly used to treat pain associated with shingles and partial seizures in people with epilepsy. The drug is believed to work by affecting calcium channels in the brain, but its full effects are not known. It comes in tablet, capsule, and liquid form, and is typically taken one to three times daily. Side effects of Neurontin include dizziness, drowsiness, and problems with coordination.

What Is Neurontin?

Neurontin® (gabapentin) is a prescription medication used to treat the following conditions:
 
  • Epilepsy -- Neurontin is approved to be used along with other seizure medications to treat partial seizures in adults and children as young as three years old.
     
  • Shingles nerve pain -- Neurontin is also approved to treat the chronic nerve pain that often occurs after an outbreak of shingles (known medically as postherpetic neuralgia).
     
(Click Neurontin Uses for more information, including possible off-label uses.)
 

Who Makes Neurontin?

It is made by Pfizer, Inc.
 

How Does It Work?

It is not known exactly how Neurontin works for nerve pain. In addition, it is not known exactly how the drug works to prevent partial seizures in people with epilepsy. It is known that it affects certain calcium channels in the brain, and this may be how it works for seizures and nerve pain.
 

Effectiveness

Several studies have looked at the effects of this medication on treating seizures and nerve pain.
 
Neurontin for Nerve Pain After Shingles
Several studies have evaluated the effectiveness of Neurontin for treating nerve pain associated with postherpetic neuralgia. People who took the drug experienced less pain compared to those not taking it. In one study, as many as 34 percent of people taking it reported having half as much pain (or less), compared to just 14 percent of a similar group of people not taking it.
Neurontin for Epilepsy
The medication was also studied as a treatment for partial seizures in people with epilepsy. These studies included people who were already taking other seizure medications and whose seizures were not adequately controlled. In one study, up to 23 percent of people who added Neurontin to their seizure medications experienced seizures half as frequently as before, compared to just 9 percent of a similar group of people who did not take the drug.
 

When and How to Take Neurontin

General considerations for when and how to take the medication include the following:
 
  • It comes in capsule and tablet form. It is taken by mouth, usually one to three times daily.
     
  • For people with difficulty swallowing tablets or capsules, a liquid form (called Neurontin solution) is also available.
     
  • The medication can be taken with or without food. If it upsets your stomach, try taking it with food.
     
  • It should be taken at the same time(s) each day to maintain an even level in your blood.
     
  • For the medication to work properly, it must be taken as prescribed. Neurontin will not work if you stop taking it.
     
  • Do not stop taking it without first discussing it with your healthcare provider (see Neurontin Withdrawal).
     

Dosing Information

The dosage that your healthcare provider recommends will vary depending on a number of factors, including:
 
  • Your age and weight
  • The medical condition being treated
  • Other medications you may be taking
  • Other medical conditions you may have.
     
As is always the case, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
 
(Click Neurontin Dosage for more information.)
 

Side Effects

As with any medicine, side effects are possible. However, not everyone who takes the drug will experience side effects. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or can easily be treated by you or your healthcare provider. Serious side effects are less common.
 
Common side effects include, but are not limited to:
 
  • Dizziness
  • Drowsiness
  • Coordination problems.
     
(Click Neurontin Side Effects to learn more, including potentially serious side effects that you should report immediately to your healthcare provider.)
 
The following eMedTV articles describe specific side effects of the drug:
 

Drug Interactions

Neurontin can potentially interact with a few other medicines (see Neurontin Drug Interactions).
 

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking this medication if you have:
 
  • Kidney disease, including kidney failure (renal failure)
  • Any allergies, including allergies to food, dyes, or preservatives.
     
Also, let your healthcare provider know if you are:
 
Make sure to tell your healthcare provider about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.
 
(Click Neurontin Warnings and Precautions to learn more, including information on who should not take the drug.)
 

What If I Take an Overdose of Neurontin?

People who take too much of this medication may have overdose symptoms that could include:
 
  • Coordination problems
  • Difficulty breathing
  • Drooping eyelids
  • Drowsiness
  • Double vision
  • Slurred speech
  • Lethargy
  • Diarrhea.
     
If you happen to overdose, seek immediate medical attention.
 
(Click Gabapentin Overdose for more information.)
 

How Should It Be Stored?

It should be stored at room temperature, away from moisture and heat. Store the medication in an airtight container.
 
Keep Neurontin and all medications out of the reach of children.
 

What Should I Do If I Miss a Dose?

If you do not take your Neurontin as scheduled, take your missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose.
 

Strengths of Neurontin

This drug is available in the following strengths and forms:
 

Is There a Generic Version of Neurontin?

Currently, both brand-name and generic versions of the medication are licensed for sale (see Generic Neurontin).
 
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
Other Articles in This eMedTV Presentation