How Does Neurontin Work?

It is not exactly clear how Neurontin® (gabapentin) works for nerve pain, nor is it known how the drug works to prevent partial seizures in people with epilepsy. Neurontin does affect certain calcium channels in the brain, and this may be how it works for seizures and nerve pain.
 
Neurontin is approved to be used along with other seizure medications to treat partial seizures in adults and children as young as three years old. It is also approved to treat the chronic nerve pain that often occurs after an outbreak of shingles (known medically as postherpetic neuralgia).
 
(For more information on how Neurontin works, click Neurontin. This article provides a complete overview of this medication, including information on its uses, general precautions, and potential side effects.)
 
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;