Epilepsy Home > Tranxene and Pregnancy
Although no specific studies have been done on Tranxene and pregnancy, because the medication is a benzodiazepine, it is not recommended for use while pregnant. Other benzodiazepines have shown problems when taken during pregnancy, such as birth defects and withdrawal symptoms. If you are taking Tranxene and pregnancy occurs, your healthcare provider will consider the benefits and risks in your situation before making a recommendation.
Tranxene and Pregnancy: An OverviewTranxene® (clorazepate dipotassium) is generally considered unsafe for use during pregnancy. It is part of a group of medications known as benzodiazepines. Studies have shown that many benzodiazepines may cause problems when used during pregnancy.
Tranxene and Pregnancy Category DThe U.S. Food and Drug Administration (FDA) uses a category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category D is given to medicines that have shown clear evidence of risk to the fetus in studies. This is a stronger warning than a pregnancy Category C classification. However, a pregnancy Category D medicine may still be given to a pregnant woman if the healthcare provider believes that the benefits to the woman outweigh the risks to the unborn child.
Tranxene was given a pregnancy Category D rating because it is a benzodiazepine. Other benzodiazepines have been shown to cause problems during pregnancy, including birth defects (when taken early in pregnancy) and withdrawal symptom in newborns (when taken later in pregnancy). Since little is known about using Tranxene during pregnancy, it is assumed that it will have the same problems as other benzodiazepines.