All generic medications must undergo certain tests to compare them to brand-name medications. The U.S. Food and Drug Administration (FDA) then looks at these tests to decide if the generic versions are equivalent to the brand-name medications and assigns a rating to each one. An "AB" rating means that the FDA has determined that a generic medication is equivalent to a brand-name medication. All of the generic Tegretol versions currently available have an "AB" rating, meaning they should be equivalent to Tegretol.
However, generic medications are allowed to have different inactive ingredients from the brand-name medication. This might include fillers, dyes, or other ingredients, which could cause problems for people with certain allergies or sensitivities. In addition, many healthcare providers prefer that their patients stay with their exact seizure medication (rather than switching back and forth between brand-name and generic versions or between different generic medications). Even small variations can make a big difference when it comes to seizure medications.
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Last reviewed by: KristiMonson, PharmD;
List of references (click here):
Tegretol and Tegretol-XR [package insert]. East Hanover, NJ: Novartis Pharmaceuticals Corporation;2009 February.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed September 25, 2009.
McKesson Corporation. Supply Management Online. Available at: https://supply.mckesson.com/portal/site/smoportal/template.LOGIN/. Accessed September 25, 2009.
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