Epilepsy Home > Primidone

Drug Interactions

Primidone can potentially interact with several other medications (see Drug Interactions With Primidone).

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking primidone if you have:
  • Porphyria
  • Anemia or any other blood disorder
  • Any allergies, including allergies to food, dyes, or preservatives.
Also, let your healthcare provider know if you are:
Make sure to tell your healthcare provider about all of the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.
(Click Precautions and Warnings With Primidone to learn more, including information on who should not take the drug.)

What If I Take an Overdose?

Little information is available regarding what exactly to expect from an overdose with primidone. Based on barbiturate overdoses (which should be similar), people who take too much may have overdose symptoms that could include:
  • Drowsiness and fatigue
  • A spinning sensation (vertigo)
  • Slurred speech
  • Coordination problems
  • Paranoia (paranoid feelings and thoughts)
  • Difficulty breathing
  • A rapid heart rate (tachycardia) or slow heart rate (bradycardia)
  • Low blood pressure (hypotension)
  • Low body temperature (hypothermia)
  • Sweating
  • Shock
  • Coma.
If you happen to take too much, seek immediate medical attention.
(Click Primidone Overdose for more information.)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
List of references (click here):
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