Epilepsy Home > Lamictal XR Drug Interactions
Lamictal XR can react with a number of products, including phenobarbital, carbamazepine, and hormonal contraceptives. Drug interactions with Lamictal XR can lead to problems such as decreased effectiveness of your medications and increased risk of side effects. Before starting treatment, make sure your healthcare provider is aware of all other medications you are taking.
An Overview of Interactions With Lamictal XRLamictal® XR™ (extended-release lamotrigine) can potentially react with a number of other medications. Some of the medicines that may lead to Lamictal XR drug interactions include:
- Carbamazepine (Carbatrol®, Epitol®, Equetro®, Tegretol®)
- Hormonal contraceptives (such as birth control pills) or hormone replacement therapy (HRT)
- Phenobarbital (Luminal®)
- Phenytoin (Dilantin®, Phenytek®)
- Primidone (Mysoline®)
- Rifampin (Rifadin®)
- Valproate medications, such as:
Lamictal XR Drug Interactions ExplainedThe following sections explain in detail the potentially negative interactions that can occur when Lamictal XR is combined with any of the medications listed above.
Carbamazepine can decrease the level of Lamictal XR in your blood, perhaps making it less effective. Your healthcare provider may recommend a higher dose of Lamictal XR if you are taking carbamazepine. In addition, using this medication may increase your risk of certain Lamictal XR side effects, such as dizziness, vision problems, or coordination problems.