Gabitril is a drug that is often prescribed to treat partial seizures. While it is not exactly clear how it prevents these seizures, it may work by enhancing the effects of gamma-aminobutyric acid (GABA), a brain chemical that is naturally calming. Gabitril comes in tablet form and is taken up to four times a day. Possible side effects include dizziness, weakness, and shakiness.
What Is Gabitril?
Gabitril® (tiagabine hydrochloride) is a prescription medication used to treat a specific type of epileptic seizure. Seizures are divided into two major categories: partial seizures (sometimes called focal seizures) and generalized seizures. Partial seizures occur in just one part of the brain, while generalized seizures affect both sides of the brain. Gabitril is approved to be used with other seizure medications to control partial seizures in people with epilepsy.
Epilepsy is a brain disorder caused by recurring, brief changes in the brain's electrical system. These changes in brain activity can lead to a seizure (see Epilepsy Symptoms).
It is not known exactly how Gabitril works to prevent partial seizures in people with epilepsy. It may work by enhancing the effects of gamma-aminobutyric acid (GABA), a brain chemical that is naturally calming. GABA can slow down the brain's electrical system, helping to control seizures. It helps to keep GABA in the parts of the brain where it is active, preventing it from being removed and enhancing its effects.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed April 10, 2012.
Briggs GG, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation. 7th ed. Philadelphia (PA): Lippincott Williams & Wilkins;2005.
National Library of Medicine (US). Drugs and Lactation Database (LactMED). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT. Accessed June 18, 2007.
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