Negative Effects of Lyrica

Most people respond well to Lyrica® (pregabalin) and do not experience any problems during the treatment process. As with any medication, however, there are possible risks associated with using this drug. Some of Lyrica's negative effects may include:
  • Lyrica is a controlled substance, meaning that it has the potential to be abused. If you have a history of drug or alcohol abuse, it may not be the best medication for you.
  • Lyrica can cause drowsiness and dizziness, so make sure to see how the drug affects you before driving or operating any machinery.
  • Lyrica can cause vision problems, especially blurred vision or double vision.
  • Studies suggest that Lyrica increases the risk of fluid retention, especially in the arms, hands, legs, and feet. This can be a sign of congestive heart failure (especially if accompanied by difficulty breathing or chest pain).
  • Lyrica can cause low platelets (a certain type of blood cell), which can increase your risk of bleeding. While you are taking Lyrica, be sure to watch for any unusual bruising or bleeding.
  • Studies suggest that Lyrica can cause an irregular heart rhythm (arrhythmia).
(Click Lyrica Side Effects and Lyrica Precautions and Warnings to learn more about the possible negative effects of this drug and for a more complete list of side effects that have been reported with this medication.)
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