Lyrica and Dry Mouth

A common side effect of Lyrica, dry mouth occurred in up to 15 percent of people who were taking the drug for postherpetic neuralgia during clinical studies. If you are taking Lyrica and dry mouth occurs, sipping water often and avoiding tobacco may provide some relief. If your dry mouth symptoms persist, be sure to talk with your healthcare provider.

An Overview of Lyrica and Dry Mouth

Dry mouth is a common side effect of Lyrica® (pregabalin), a prescription medication used to treat certain types of nerve pain and epileptic seizures. In previous clinical studies, up to 15 percent of people taking Lyrica for postherpetic neuralgia treatment reported having a dry mouth, compared to just 3 percent of those not taking Lyrica. Dry mouth was most common in people taking the highest Lyrica dosage; it was less common in those taking lower doses. Dry mouth was also less common in people taking Lyrica for treating diabetic neuropathy, fibromyalgia, seizures, or nerve pain due to spinal cord injury.

Suggestions for Lyrica and Dry Mouth

If you are taking Lyrica and dry mouth becomes a problem, there are a few things that you can do. Some of these suggestions include:
  • Sipping water or sugarless drinks during meals. This will make chewing and swallowing easier; it may also improve the taste of food.
  • Avoiding drinks with caffeine, such as coffee, tea, and some sodas. Caffeine can dry out the mouth.
  • Being aware of spicy or salty foods, because they may cause pain in a dry mouth.
  • Chewing sugarless gum or sucking on sugarless hard candy to stimulate saliva flow; cinnamon- or mint-flavored candies are good choices.
  • Avoiding tobacco and alcohol, because they dry out the mouth.
  • Using a humidifier at night.
  • Sipping water or sugarless drinks often.
If you develop dry mouth while taking Lyrica and the suggestions above do not help, make sure to talk with your healthcare provider. There is treatment that he or she may be able to recommend, such as artificial saliva. Also, depending on how severe your dry mouth side effects are, he or she may also recommend that you adjust your Lyrica dosage or try a different medication.
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