Dilantin Drug Interactions (Cont.)

 
Phenothiazines
Phenothiazines can increase the amount of Dilantin in your blood, increasing your risk of side effects. Your healthcare provider may need to measure the level of Dilantin in your blood and adjust your dose as necessary.
 
Quinidine
Dilantin may make quinidine less effective. If you are taking these drugs together, your healthcare provider may need to increase your quinidine dosage.
 
Reserpine
Reserpine can decrease the amount of Dilantin in your blood, perhaps making it less effective. If you are taking these drugs together, your healthcare provider may need to measure your Dilantin level (using a blood test) and adjust your dose as necessary.
 
Rifampin (Rifadin)
Dilantin may make rifampin less effective. If you are taking these drugs together, your healthcare provider may need to increase your rifampin dosage.
 
Salicylates
Salicylates can increase the amount of Dilantin in your blood, increasing your risk of side effects. Your healthcare provider may need to measure the level of Dilantin in your blood and adjust your dose as necessary.
 
Sucralfate (Carafate)
Sucralfate can decrease the amount of Dilantin in your blood, perhaps making it less effective. If you are taking these drugs together, your healthcare provider may need to measure your Dilantin level (using a blood test) and adjust your dose as necessary.
 
Sulfonamides
Sulfonamides can increase the amount of Dilantin in your blood, increasing your risk of side effects. Your healthcare provider may need to measure the level of Dilantin in your blood and adjust your dose as necessary.
 
Ticlopidine (Ticlid)
Ticlopidine can increase the amount of Dilantin in your blood, increasing your risk of side effects. Your healthcare provider may need to measure the level of Dilantin in your blood and adjust your dose as necessary.
(Dilantin Drug Interactions Continued: Page 6)

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;