- Bipolar disorder -- carbamazepine is approved to treat manic or mixed episodes (which include characteristics of both mania and depression) associated with bipolar disorder, also known as manic depression.
- Epilepsy -- carbamazepine is approved to treat various types of seizures, though it is usually not effective at treating absence seizures (petit mal seizures).
- Trigeminal neuralgia -- carbamazepine is approved to treat pain associated with trigeminal neuralgia (also known as tic douloureux), a nerve condition that causes episodes of facial pain (typically cheek or jaw pain).
Not all forms of carbamazepine are approved for each of the above uses. Equetro is approved to treat bipolar disorder only, while Carbatrol, Epitol, Tegretol, and generic carbamazepine are approved to treat epilepsy and trigeminal neuralgia (but not bipolar disorder).