Carbamazepine Drug Interactions

Hormone Contraceptives
Carbamazepine may make hormone contraceptives (including birth control pills, implants, patches, and rings) less effective, increasing your chances of pregnancy. Talk with your healthcare provider about non-hormonal forms of contraception (such as condoms).
 
Lithium (Eskalith, Lithobid)
Combining lithium with carbamazepine can increase your risk of side effects. Talk with your healthcare provider before taking these medications together.
 
Monoamine Oxidase Inhibitors (MAOIs)
In general, you should not take monoamine oxidase inhibitors (MAOIs) and carbamazepine together. Before you can take carbamazepine, you need to stop taking an MAOI for at least 14 days.
 
Nefazodone (Serzone)
Carbamazepine and nefazodone should not be taken together. Carbamazepine can significantly decrease the level of nefazodone in your blood, possibly making nefazodone ineffective.
 
Niacin (Niacor, Niaspan)
Niacin products (including non-prescription niacin) can raise the level of carbamazepine in your blood, increasing your risk of side effects. Be aware that many B-complex vitamins contain niacin. Talk with your healthcare provider before taking niacin and carbamazepine together.
 
Other Seizure Medications
Some other seizure medications may increase or decrease the level of carbamazepine in your blood. Also, carbamazepine can increase or decrease the levels of other seizure medications in your blood. Your healthcare provider should monitor you closely if you take carbamazepine in combination with other seizure medications.
 
Propoxyphene (Darvon, Darvocet)
Propoxyphene can raise the level of carbamazepine in your blood, increasing your risk of side effects. Talk with your healthcare provider before taking these medications together.
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